Chemical genomic profiling for antimalarial therapies, response signatures and molecular targets

Malaria remains a devastating disease largely because of widespread drug resistance. New drugs and a better understanding of the mechanisms of drug action and resistance are essential for fulfilling the promise of eradicating malaria. Using high-throughput chemical screening and genome-wide associat...

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Bibliografiske detaljer
Main Authors: Yuan, Jing, Cheng, Ken Chih-Chien, Johnson, Ronald L., Huang, Ruili, Pattaradilokrat, Sittiporn, Liu, Anna, Guha, Rajarshi, Fidock, David, Inglese, James, Wellems, Thomas E., Austin, Christopher P., Su, Xin-zhuan
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396183/
https://ncbi.nlm.nih.gov/pubmed/21817045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1205216
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