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Nucleoprotein filament formation is the structural basis for bacterial protein H-NS gene silencing

H-NS is an abundant nucleoid-associated protein in bacteria that globally silences genes, including horizontally-acquired genes related to pathogenesis. Although it has been shown that H-NS has multiple modes of DNA-binding, which mode is employed in gene silencing is still unclear. Here, we report...

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Detalhes bibliográficos
Main Authors: Lim, Ci Ji, Lee, Sin Yi, Kenney, Linda J., Yan, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396134/
https://ncbi.nlm.nih.gov/pubmed/22798986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00509
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