Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criteria for Alzheimer’s disease

BACKGROUND: The promise of Alzheimer’s disease (AD) biomarkers has led to their incorporation in new diagnostic criteria and in therapeutic trials; however, significant barriers exist to widespread use. Chief among these is the lack of internationally accepted standards for quantitative metrics. Hip...

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Detalhes bibliográficos
Main Authors: Jack, Clifford R, Barkhof, Frederik, Bernstein, Matt A, Cantillon, Marc, Cole, Patricia E, DeCarli, Charles, Dubois, Bruno, Duchesne, Simon, Fox, Nick C, Frisoni, Giovanni B, Hampel, Harald, Hill, Derek LG, Johnson, Keith, Mangin, Jean-François, Scheltens, Philip, Schwarz, Adam J, Sperling, Reisa, Suhy, Joyce, Thompson, Paul M, Weiner, Michael, Foster, Norman L
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396131/
https://ncbi.nlm.nih.gov/pubmed/21784356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2011.04.007
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