Suppressive Regulation of KSHV RTA with O-GlcNAcylation

BACKGROUND: The replication and transcription activator (RTA) of Kaposi's sarcoma-associated herpesvirus (KSHV) is a molecular switch that initiates a productive replication of latent KSHV genomes. KSHV RTA (K-RTA) is composed of 691 amino acids with high Ser and Thr content (17.7%), but to wha...

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Autors principals: Ko, Ying-Chieh, Tsai, Wan-Hua, Wang, Pei-Wen, Wu, I-Lin, Lin, Shu-Yu, Chen, Yu-Lian, Chen, Jen-Yang, Lin, Su-Fang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395832/
https://ncbi.nlm.nih.gov/pubmed/22300411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-12
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