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Differential effects of dimethylsulfoxide on the activities of human DNA polymerases alpha and delta.

The effects of dimethylsulfoxide on the activities of purified human placental DNA polymerase alpha and DNA polymerase delta were examined. DNA polymerase alpha was inhibited by dimethylsulfoxide, whereas DNA polymerase delta was significantly activated, by as much as 6-fold. Kinetic data show that...

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Autors principals: Lee, M Y, Toomey, N L
Format: Artigo
Idioma:Inglês
Publicat: 1986
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC339568/
https://ncbi.nlm.nih.gov/pubmed/3951994
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