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Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa

Eight kinds of gene-disrupted mice (Clgn, Calr3, Pdilt, Tpst2, Ace, Adam1a, Adam2, and Adam3) show impaired sperm transition into the oviducts and defective sperm binding to the zona pellucida. All of these knockout strains are reported to lack or show aberrant expression of a disintegrin and metall...

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Autores principales: Yamaguchi, Ryo, Fujihara, Yoshitaka, Ikawa, Masahito, Okabe, Masaru
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395656/
https://ncbi.nlm.nih.gov/pubmed/22621904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1025
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