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A secretagogue-siRNA conjugate confers resistance to cytotoxicity in a cell model of Sjögren's syndrome

OBJECTIVE: Sjögren's syndrome (SjS) is characterized by xerophthalmia and xerostomia resulting from loss of secretory function due to immune cell infiltration in lacrimal and salivary glands. Current SjS therapeutic strategies employ secretagogues to induce secretion via muscarinic receptor sti...

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Detalhes bibliográficos
Main Authors: Pauley, Kaleb M., Gauna, Adrienne E., Grichtchenko, Irina I., Chan, Edward K.L., Cha, Seunghee
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395589/
https://ncbi.nlm.nih.gov/pubmed/21567383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30450
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