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Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling
The placenta is a hematopoietic organ that supports hematopoietic stem/progenitor cell (HSPC) generation and expansion without promoting differentiation. We identified PDGF-B signaling in trophoblasts as a key component of the unique placental hematopoietic microenvironment that protects HSPCs from...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395466/ https://ncbi.nlm.nih.gov/pubmed/22387002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.12.022 |
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