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Spatial Positive Feedback at the Onset of Mitosis
Mitosis is triggered by the activation of Cdk1-cyclin B1 and its translocation from the cytoplasm to the nucleus. Positive feedback loops regulate the activation of Cdk1-cyclin B1 and help make the process irreversible and all-or-none in character. Here we examine whether an analogous process, spati...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395376/ https://ncbi.nlm.nih.gov/pubmed/22726437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.028 |
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