A combined DPA1∼DPB1 amino acid epitope is the primary unit of selection on the HLA-DP heterodimer

Here, we present results for DPA1 and DPB1 four-digit allele-level typing in a large (n = 5,944) sample of unrelated European American stem cell donors previously characterized for other class I and class II loci. Examination of genetic data for both chains of the DP heterodimer in the largest cohor...

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Autori principali: Hollenbach, Jill A., Madbouly, Abeer, Gragert, Loren, Vierra-Green, Cynthia, Flesch, Susan, Spellman, Stephen, Begovich, Ann, Noreen, Harriet, Trachtenberg, Elizabeth, Williams, Tom, Yu, Neng, Shaw, Bronwen, Fleischhauer, Katharina, Fernandez-Vina, Marcelo, Maiers, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2012
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395342/
https://ncbi.nlm.nih.gov/pubmed/22526601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-012-0615-3
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