The Chemical Interplay between Nitric Oxide and Mitochondrial Cytochrome c Oxidase: Reactions, Effectors and Pathophysiology

Nitric oxide (NO) reacts with Complex I and cytochrome c oxidase (CcOX, Complex IV), inducing detrimental or cytoprotective effects. Two alternative reaction pathways (PWs) have been described whereby NO reacts with CcOX, producing either a relatively labile nitrite-bound derivative (CcOX-NO(2)  (−)...

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Hlavní autoři: Sarti, Paolo, Forte, Elena, Giuffrè, Alessandro, Mastronicola, Daniela, Magnifico, Maria Chiara, Arese, Marzia
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
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Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395247/
https://ncbi.nlm.nih.gov/pubmed/22811713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/571067
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