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The potential of Fas ligand (apoptosis-inducing molecule) as an unconventional therapeutic target in type 1 diabetes

The development of type 1 diabetes (T1D) is driven by autoreactive T cells that attack and destroy the insulin-producing β-cells in pancreatic islets, forcing patients to take multiple daily insulin injections. Insulin therapy, however, is not a cure and diabetic patients often develop serious long-...

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Main Authors: Hamad, Abdel Rahim A.R, Arcara, Kristin, Uddin, Sophia, Donner, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395106/
https://ncbi.nlm.nih.gov/pubmed/22807927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00196
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