Chd2 interacts with H3.3 to determine myogenic cell fate

Cell differentiation is mediated by lineage-determining transcription factors. We show that chromodomain helicase DNA-binding domain 2 (Chd2), a SNF2 chromatin remodelling enzyme family member, interacts with MyoD and myogenic gene regulatory sequences to specifically mark these loci via deposition...

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Auteurs principaux: Harada, Akihito, Okada, Seiji, Konno, Daijiro, Odawara, Jun, Yoshimi, Tomohiko, Yoshimura, Saori, Kumamaru, Hiromi, Saiwai, Hirokazu, Tsubota, Toshiaki, Kurumizaka, Hitoshi, Akashi, Koichi, Tachibana, Taro, Imbalzano, Anthony N, Ohkawa, Yasuyuki
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395093/
https://ncbi.nlm.nih.gov/pubmed/22569126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.136
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