Cumulative Exposure to CD8+ Granzyme B(hi) T cells Is Associated With Reduced Lung Function Early after Lung Transplantation

Outcomes following lung transplant remain suboptimal. This is attributable to variable post-transplant recovery of lung function, and inconsistent degrees of lung function loss after peak function is reached. Granzyme B is elevated in the blood and bronchoalveolar lavage (BAL) in acute rejection. We...

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Autori principali: Mohammed, A, Ulukpo, O, Lawrence, EC, Fernandez, F, Pickens, A, Gal, AA, Force, SD, Easley, KC, Larsen, CP, Kirk, AD, Neujahr, DC
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395055/
https://ncbi.nlm.nih.gov/pubmed/22172867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2011.09.072
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