A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens

BACKGROUND: KRAS mutation testing is required to select patients with metastatic colorectal cancer (CRC) to receive anti-epidermal growth factor receptor antibodies, but the optimal KRAS mutation test method is uncertain. METHODS: We conducted a two-site comparison of two commercial KRAS mutation ki...

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Detalhes bibliográficos
Main Authors: Gonzalez de Castro, D, Angulo, B, Gomez, B, Mair, D, Martinez, R, Suarez-Gauthier, A, Shieh, F, Velez, M, Brophy, V H, Lawrence, H J, Lopez-Rios, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394984/
https://ncbi.nlm.nih.gov/pubmed/22713664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.259
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