A human gastric carcinoma contains a single mutated and an amplified normal allele of the Ki-ras oncogene.

The DNA from various human tumors and tumor cell lines was screened for the presence of mutated ras oncogenes with synthetic oligonucleotide probes, as well as with the NIH/3T3 cell transfection assay. Among the various mutations found we discovered two novel Ki-ras mutations in codon 12: gly to ala...

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Publicado en:Nucleic Acids Res
Autores principales: Bos, J L, Verlaan-de Vries, M, Marshall, C J, Veeneman, G H, van Boom, J H, van der Eb, A J
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1986
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339498/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3951985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.3.1209
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