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The Role of Structural Disorder in the Rewiring of Protein Interactions through Evolution

Structurally disordered regions play a key role in protein-protein interaction networks and the evolution of highly connected proteins, enabling the molecular mechanisms for multiple binding. However, the role of protein disorder in the evolution of interaction networks has only been investigated th...

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Detalhes bibliográficos
Main Authors: Mosca, Roberto, Pache, Roland A., Aloy, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394948/
https://ncbi.nlm.nih.gov/pubmed/22389433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.014969
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