Use of Proteinase K Nonspecific Digestion for Selective and Comprehensive Identification of Interpeptide Cross-links: Application to Prion Proteins

Chemical cross-linking combined with mass spectrometry is a rapidly developing technique for structural proteomics. Cross-linked proteins are usually digested with trypsin to generate cross-linked peptides, which are then analyzed by mass spectrometry. The most informative cross-links, the interpept...

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Bibliografische gegevens
Hoofdauteurs: Petrotchenko, Evgeniy V., Serpa, Jason J., Hardie, Darryl B., Berjanskii, Mark, Suriyamongkol, Bow P., Wishart, David S., Borchers, Christoph H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2012
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394941/
https://ncbi.nlm.nih.gov/pubmed/22438564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013524
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