POTENTIAL FACTORS INFLUENCING THE DEVELOPMENT OF THROMBOCYTOPENIA AND CONSUMPTIVE COAGULOPATHY AFTER GENETICALLY-MODIFIED PIG LIVER XENOTRANSPLANTATION

Upregulation of tissue factor (TF) expression on activated donor endothelial cells (ECs) triggered by the immune response (IR) has been considered the main initiator of consumptive coagulopathy (CC). In this study, we aimed to identify potential factors in the development of thrombocytopenia and CC...

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Main Authors: Ekser, Burcin, Lin, Chih Che, Long, Cassandra, Echeverri, Gabriel J., Hara, Hidetaka, Ezzelarab, Mohamed, Bogdanov, Vladimir Y., Stolz, Donna B., Enjyoji, Keiichi, Robson, Simon C., Ayares, David, Dorling, Anthony, Cooper, David K.C., Gridelli, Bruno
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394909/
https://ncbi.nlm.nih.gov/pubmed/22642260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1432-2277.2012.01506.x
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