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Estrogen Regulates Hepcidin Expression via GPR30-BMP6-Dependent Signaling in Hepatocytes

Hepcidin, a liver-derived iron regulatory protein, plays a crucial role in iron metabolism. It is known that gender differences exist with respect to iron storage in the body; however, the effects of sex steroid hormones on iron metabolism are not completely understood. We focused on the effects of...

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Hlavní autoři: Ikeda, Yasumasa, Tajima, Soichiro, Izawa-Ishizawa, Yuki, Kihira, Yoshitaka, Ishizawa, Keisuke, Tomita, Shuhei, Tsuchiya, Koichiro, Tamaki, Toshiaki
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394730/
https://ncbi.nlm.nih.gov/pubmed/22792339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040465
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