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Targeted Administration into the Suprachoroidal Space Using a Microneedle for Drug Delivery to the Posterior Segment of the Eye

PURPOSE. This study seeks to determine the intraocular pharmacokinetics of molecules and particles injected into the suprachoroidal space of the rabbit eye in vivo using a hollow microneedle. METHODS. Suprachoroidal injections of fluorescein and fluorescently tagged dextrans (40 and 250 kDa), bevaci...

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Detalhes bibliográficos
Main Authors: Patel, Samirkumar R., Berezovsky, Damian E., McCarey, Bernard E., Zarnitsyn, Vladimir, Edelhauser, Henry F., Prausnitz, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394664/
https://ncbi.nlm.nih.gov/pubmed/22669719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9872
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