Gene-carried hepatoma targeting complex induced high gene transfection efficiency with low toxicity and significant antitumor activity

BACKGROUND: The success of gene transfection is largely dependent on the development of a vehicle or vector that can efficiently deliver a gene to cells with minimal toxicity. METHODS: A liver cancer-targeted specific peptide (FQHPSF sequence) was successfully synthesized and linked with chitosan-li...

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Detalhes bibliográficos
Main Authors: Zhao, Qing-Qing, Hu, Yu-Lan, Zhou, Yang, Li, Ni, Han, Min, Tang, Gu-Ping, Qiu, Feng, Tabata, Yasuhiko, Gao, Jian-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394466/
https://ncbi.nlm.nih.gov/pubmed/22811604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S30909
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