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Towards accurate detection and genotyping of expressed variants from whole transcriptome sequencing data

BACKGROUND: Massively parallel transcriptome sequencing (RNA-Seq) is becoming the method of choice for studying functional effects of genetic variability and establishing causal relationships between genetic variants and disease. However, RNA-Seq poses new technical and computational challenges comp...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Duitama, Jorge, Srivastava, Pramod K, Măndoiu, Ion I
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394419/
https://ncbi.nlm.nih.gov/pubmed/22537301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S2-S6
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