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(18)F-Fluromisonidazole PET Imaging as a Biomarker for the Response to 5,6-Dimethylxanthenone-4-Acetic Acid in Colorectal Xenograft Tumors

The aim of this study was to evaluate (18)F-fluromisonidazole ((18)F-FMISO) PET for monitoring the tumor response to the antivascular compound 5,6-dimethylxanthenone-4-acetic acid (DMXAA; vadimezan). METHODS: (18)F-FMISO PET was performed 3 h before and 24 h after treatment with DMXAA (20 mg/kg) in...

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Main Authors: Oehler, Christoph, O’Donoghue, Joseph A., Russell, James, Zanzonico, Pat, Lorenzen, Sylvie, Ling, C. Clifton, Carlin, Sean
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394183/
https://ncbi.nlm.nih.gov/pubmed/21321262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.110.081372
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