Influence of CYP2B6 and ABCB1 SNPs on nevirapine plasma concentrations in Burundese HIV-positive patients using dried sample spot devices

AIMS: The pharmacokinetics (PK) and pharmacogenetics (PG) of nevirapine have been studied in rich and limited-resource countries. CYP2B6 single nucleotide polymorphisms (SNPs) have been associated with decreased drug clearance. We evaluated the PG determinants of nevirapine trough concentrations in...

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Hauptverfasser: Calcagno, Andrea, D'Avolio, Antonio, Simiele, Marco, Cusato, Jessica, Rostagno, Roberto, Libanore, Valentina, Baietto, Lorena, Siccardi, Marco, Bonora, Stefano, Di Perri, Giovanni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2012
Schlagworte:
Pharmacogenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394137/
https://ncbi.nlm.nih.gov/pubmed/22680342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04163.x
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