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Inhibition of N-Myc down regulated gene 1 in in vitro cultured human glioblastoma cells

AIM: To study short dsRNA oligonucleotides (siRNA) as a potent tool for artificially modulating gene expression of N-Myc down regulated gene 1 (NDRG1) gene induced under different physiological conditions (Normoxia and hypoxia) modulating NDRG1 transcription, mRNA stability and translation. METHODS:...

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Hlavní autoři: Said, Harun M, Polat, Buelent, Stein, Susanne, Guckenberger, Mathias, Hagemann, Carsten, Staab, Adrian, Katzer, Astrid, Anacker, Jelena, Flentje, Michael, Vordermark, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Co., Limited 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394081/
https://ncbi.nlm.nih.gov/pubmed/22787578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v3.i7.104
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