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Paradoxical relationship between degree of EGFR amplification and outcome in glioblastomas

Glioblastoma (GBM) is the most common primary brain tumor in adults and often has amplification of the Epidermal Growth Factor Receptor (EGFR) gene. The value of EGFR as a prognostic marker in GBMs is unclear; some studies have shown an adverse correlation, while others indicated a neutral or even f...

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Hlavní autoři: Hobbs, Jonathan, Nikiforova, Marina N., Fardo, David W., Bortoluzzi, Stephanie, Cieply, Kathleen, Hamilton, Ronald L., Horbinski, Craig
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393818/
https://ncbi.nlm.nih.gov/pubmed/22472960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e3182518e12
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