Dietary fat-induced taurocholic acid production promotes pathobiont and colitis in IL-10(−/−) mice

The composite human microbiome of Western populations has likely changed over the past century, brought on by new environmental triggers that often have a negative impact on human health(1). Here we show that consumption of a diet high in saturated (milk derived)-fat (MF), but not polyunsaturated (s...

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Main Authors: Devkota, Suzanne, Wang, Yunwei, Musch, Mark, Leone, Vanessa, Fehlner-Peach, Hannah, Nadimpalli, Anuradha, Antonopoulos, Dionysios A., Jabri, Bana, Chang, Eugene B.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393783/
https://ncbi.nlm.nih.gov/pubmed/22722865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11225
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