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Fragile X syndrome: Mechanistic insights and therapeutic avenues regarding the role of potassium channels

Fragile X syndrome (FXS) is a common form of mental disability and one of the known causes of autism. The mutation responsible for FXS is a large expansion of the trinucleotide CGG repeats which leads to DNA methylation of the fragile X mental retardation gene 1 (FMR1) and transcriptional silencing,...

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Bibliografski detalji
Glavni autori: Lee, Hye Young, Jan, Lily Yeh
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393774/
https://ncbi.nlm.nih.gov/pubmed/22483378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2012.03.010
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