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An Improved Genetically Encoded Red Fluorescent Ca(2+) Indicator for Detecting Optically Evoked Action Potentials
Genetically encoded Ca(2+) indicators (GECIs) are powerful tools to image activities of defined cell populations. Here, we developed an improved red fluorescent GECI, termed R-CaMP1.07, by mutagenizing R-GECO1. In HeLa cell assays, R-CaMP1.07 exhibited a 1.5–2-fold greater fluorescence response comp...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393713/ https://ncbi.nlm.nih.gov/pubmed/22808076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039933 |
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