Campylobacter jejuni Induces Acute Enterocolitis in Gnotobiotic IL-10(−/−) Mice via Toll-Like-Receptor-2 and -4 Signaling

BACKGROUND: Campylobacter jejuni is a leading cause of foodborne bacterial enterocolitis worldwide. Investigation of immunopathology is hampered by a lack of suitable vertebrate models. We have recently shown that gnotobiotic mice as well as conventional IL-10(−/−) animals are susceptible to C. jeju...

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Autores principales: Haag, Lea-Maxie, Fischer, André, Otto, Bettina, Plickert, Rita, Kühl, Anja A., Göbel, Ulf B., Bereswill, Stefan, Heimesaat, Markus M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393706/
https://ncbi.nlm.nih.gov/pubmed/22808254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040761
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