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Insights into dynein motor domain function from a 3.3 Å crystal structure
Dyneins power the beating of cilia and flagella, transport various intracellular cargos and are important during mitosis. All dyneins have a ~300kDa motor domain consisting of a ring of six AAA+ domains. ATP hydrolysis in the AAA+ ring drives the cyclic relocation of a motile element, the linker dom...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393637/ https://ncbi.nlm.nih.gov/pubmed/22426545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2272 |
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