The Epstein-Barr Virus (EBV)-Induced Tumor Suppressor MicroRNA MiR-34a Is Growth Promoting in EBV-Infected B Cells

Epstein-Barr virus (EBV) infection of primary human B cells drives their indefinite proliferation into lymphoblastoid cell lines (LCLs). B cell immortalization depends on expression of viral latency genes, as well as the regulation of host genes. Given the important role of microRNAs (miRNAs) in reg...

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Bibliographic Details
Main Authors: Forte, Eleonora, Salinas, Raul E., Chang, Christina, Zhou, Ting, Linnstaedt, Sarah D., Gottwein, Eva, Jacobs, Cassandra, Jima, Dereje, Li, Qi-Jing, Dave, Sandeep S., Luftig, Micah A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Transformation and Oncogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393554/
https://ncbi.nlm.nih.gov/pubmed/22496226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07056-11
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