Epstein-Barr Virus Latent Membrane Protein 2A Promotes Invasion of Nasopharyngeal Carcinoma Cells through ERK/Fra-1-Mediated Induction of Matrix Metalloproteinase 9

Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) is highly metastatic, and this malignant feature may be promoted by an EBV oncoprotein, latent membrane protein 2A (LMP2A). Acting as a signal regulator, LMP2A can enhance invasiveness and motility of epithelial cells. Downstream fro...

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Hlavní autoři: Lan, Yu-Yan, Hsiao, Jenn-Ren, Chang, Kung-Chao, Chang, Jeffrey Shu-Ming, Chen, Chaio-Wei, Lai, Hsiao-Ching, Wu, Shih-Yi, Yeh, Tzu-Hao, Chang, Fang-Hsin, Lin, Wei-Hung, Su, Ih-Jen, Chang, Yao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Transformation and Oncogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393536/
https://ncbi.nlm.nih.gov/pubmed/22514348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00174-12
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