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In Vitro Activity of MK-7655, a Novel β-Lactamase Inhibitor, in Combination with Imipenem against Carbapenem-Resistant Gram-Negative Bacteria

Carbapenem-resistant bacteria represent a significant treatment challenge due to the lack of active antimicrobials available. MK-7655 is a novel β-lactamase inhibitor under clinical development. We investigated the combined killing activity of imipenem and MK-7655 against four imipenem-resistant bac...

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Detalhes bibliográficos
Main Authors: Hirsch, Elizabeth B., Ledesma, Kimberly R., Chang, Kai-Tai, Schwartz, Michael S., Motyl, Mary R., Tam, Vincent H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393460/
https://ncbi.nlm.nih.gov/pubmed/22526311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05927-11
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