Efficacy of Bacteriophage Therapy in Experimental Sepsis and Meningitis Caused by a Clone O25b:H4-ST131 Escherichia coli Strain Producing CTX-M-15

We evaluated phage therapy in experimental infections due to S242, a fatal neonatal meningitis Escherichia coli strain belonging to the worldwide-distributed O25b:H4-ST131 clone that produces extended-spectrum beta-lactamase CTX-M-15. A lytic phage, EC200(PP), active against S242, was isolated from...

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Autors principals: Pouillot, Flavie, Chomton, Maryline, Blois, Hélène, Courroux, Celine, Noelig, Julien, Bidet, Philippe, Bingen, Edouard, Bonacorsi, Stéphane
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393425/
https://ncbi.nlm.nih.gov/pubmed/22491690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06330-11
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