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Dual Roles of FmtA in Staphylococcus aureus Cell Wall Biosynthesis and Autolysis

The fmtA gene is a member of the Staphylococcus aureus core cell wall stimulon. The FmtA protein interacts with β-lactams through formation of covalent species. Here, we show that FmtA has weak d-Ala-d-Ala-carboxypeptidase activity and is capable of covalently incorporating C14-Gly into cell walls....

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Bibliographic Details
Main Authors: Qamar, Aneela, Golemi-Kotra, Dasantila
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393393/
https://ncbi.nlm.nih.gov/pubmed/22564846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00187-12
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