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On the Prevention and Analysis of Missing Data in Randomized Clinical Trials: The State of the Art

ABSTRACT: We summarize and elaborate on the recently published National Research Council report entitled “The Prevention and Treatment of Missing Data in Clinical Trials.” We tailor our discussion to orthopaedic trials. In particular, we discuss the intent-to-treat principle, review study design and...

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Detalhes bibliográficos
Main Authors: Scharfstein, Daniel O., Hogan, Joseph, Herman, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: Journal of Bone and Joint Surgery, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393113/
https://ncbi.nlm.nih.gov/pubmed/22810454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.L.00273
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