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Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

Physiological oxidants that are generated by activated phagocytes comprise the main source of oxidative stress during inflammation(1,2). Oxidants such as taurine chloramine (TnCl) and hydrogen peroxide (H(2)O(2)) can damage proteins and induce apoptosis, but the role of specific protein oxidation in...

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Bibliographische Detailangaben
Hauptverfasser: Klamt, Fábio, Zdanov, Stéphanie, Levine, Rodney L., Pariser, Ashley, Zhang, Yaqin, Zhang, Baolin, Yu, Li-Rong, Veenstra, Timothy D., Shacter, Emily
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393095/
https://ncbi.nlm.nih.gov/pubmed/19734890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1968
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