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Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

Physiological oxidants that are generated by activated phagocytes comprise the main source of oxidative stress during inflammation(1,2). Oxidants such as taurine chloramine (TnCl) and hydrogen peroxide (H(2)O(2)) can damage proteins and induce apoptosis, but the role of specific protein oxidation in...

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Detalhes bibliográficos
Main Authors: Klamt, Fábio, Zdanov, Stéphanie, Levine, Rodney L., Pariser, Ashley, Zhang, Yaqin, Zhang, Baolin, Yu, Li-Rong, Veenstra, Timothy D., Shacter, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393095/
https://ncbi.nlm.nih.gov/pubmed/19734890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1968
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