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A novel role for type 1 angiotensin receptors on T lymphocytes to limit target organ damage in hypertension

RATIONALE: Human clinical trials using type 1 angiotensin (AT(1)) receptor antagonists indicate that angiotensin II is a critical mediator of cardiovascular and renal disease. However, recent studies have suggested that individual tissue pools of AT(1) receptors may have divergent effects on target...

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Autores principales: Zhang, Jian-dong, Patel, Mehul B., Song, Young-Soo, Griffiths, Robert, Burchette, James, Ruiz, Phillip, Sparks, Matthew A., Yan, Ming, Howell, David N., Gomez, Jose A., Spurney, Robert F., Wilson, Christopher B., Coffman, Thomas M., Crowley, Steven D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393036/
https://ncbi.nlm.nih.gov/pubmed/22534490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.261768
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