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Human Erythropoietin Gene Delivery Using an Arginine-grafted Bioreducible Polymer System

Erythropoiesis-stimulating agents are widely used to treat anemia for chronic kidney disease (CKD) and cancer, however, several clinical limitations impede their effectiveness. Nonviral gene therapy systems are a novel solution to these problems as they provide stable and low immunogenic protein exp...

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Autors principals: Lee, Youngsook, Nam, Hye Yeong, Kim, Jaesung, Lee, Minhyung, Yockman, James W, Shin, Sug Kyun, Kim, Sung Wan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392991/
https://ncbi.nlm.nih.gov/pubmed/22472948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.62
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