Modeling schizophrenia using hiPSC neurons

Schizophrenia (SCZD) is a debilitating neurological disorder with a world-wide prevalence of 1%; there is a strong genetic component, with an estimated heritability of 80–85%(1). Though postmortem studies have revealed reduced brain volume, cell size, spine density and abnormal neural distribution i...

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Detalhes bibliográficos
Main Authors: Brennand, Kristen, Simone, Anthony, Jou, Jessica, Gelboin-Burkhart, Chelsea, Tran, Ngoc, Sangar, Sarah, Li, Yan, Mu, Yangling, Chen, Gong, Yu, Diana, McCarthy, Shane, Sebat, Jonathan, Gage, Fred H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392969/
https://ncbi.nlm.nih.gov/pubmed/21490598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09915
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