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Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells

Addition of actin monomer (G-actin) to growing actin filaments (F-actin) at the leading edge generates force for cell locomotion. The polymerization reaction and its regulation have been studied in depth. However, the mechanism responsible for transport of G-actin substrate to the cell front is larg...

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Detalhes bibliográficos
Main Authors: Fan, Yi, Eswarappa, Sandeepa M., Hitomi, Masahiro, Fox, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392929/
https://ncbi.nlm.nih.gov/pubmed/22778278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111088
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