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Stochastic model search with binary outcomes for genome-wide association studies

OBJECTIVE: The spread of case–control genome-wide association studies (GWASs) has stimulated the development of new variable selection methods and predictive models. We introduce a novel Bayesian model search algorithm, Binary Outcome Stochastic Search (BOSS), which addresses the model selection pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Russu, Alberto, Malovini, Alberto, Puca, Annibale A, Bellazzi, Riccardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392850/
https://ncbi.nlm.nih.gov/pubmed/22534080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2011-000741
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