Serum COMP-C3b complexes in rheumatic diseases and relation to anti-TNF-α treatment

INTRODUCTION: Cartilage oligomeric matrix protein (COMP) is found at elevated concentrations in sera of patients with joint diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). We recently showed that COMP activates complement via the alternative pathway and that COMP-C3b complexes ar...

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Detalhes bibliográficos
Main Authors: Happonen, Kaisa E, Saxne, Tore, Geborek, Pierre, Andersson, Maria, Bengtsson, Anders A, Hesselstrand, Roger, Heinegård, Dick, Blom, Anna M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392805/
https://ncbi.nlm.nih.gov/pubmed/22264230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3694
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