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Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent Mechanisms

OBJECTIVE: Nicotinic acid (NA) treatment has been associated with benefits in atherosclerosis that are usually attributed to effects on plasma lipoproteins. The NA receptor GPR109A is expressed in monocytes and macrophages, suggesting a possible additional role for NA in modulating function of these...

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Detalhes bibliográficos
Main Authors: Digby, Janet E., Martinez, Fernando, Jefferson, Andrew, Ruparelia, Neil, Chai, Joshua, Wamil, Malgorzata, Greaves, David R., Choudhury, Robin P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392598/
https://ncbi.nlm.nih.gov/pubmed/22267479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.241836
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