Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis.()

Lupus nephritis (LN) is a serious manifestation of SLE. Therapeutic studies in mouse LN models do not always predict outcomes of human therapeutic trials, raising concerns about the human relevance of these pre-clinical models. In this study we used an unbiased transcriptional network approach to de...

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Main Authors: Berthier, Celine C, Bethunaickan, Ramalingam, Gonzalez-Rivera, Tania, Nair, Viji, Ramanujam, Meera, Zhang, Weijia, Bottinger, Erwin P., Segerer, Stephan, Lindenmeyer, Maja, Cohen, Clemens D., Davidson, Anne, Kretzler, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392438/
https://ncbi.nlm.nih.gov/pubmed/22723521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103031
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