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ROLE OF S-1-P RECEPTORS AND HUMAN VASCULAR SMOOTH MUSCLE CELL MIGRATION IN DIABETES AND METABOLIC SYNDROME

BACKGROUND: Sphingosine-1-phosphate (S-1-P) is a bioactive sphingolipid released from activated platelets that stimulates migration of vascular smooth muscle cells (VSMC) in vitro. S-1-P is associated with oxidized low-density lipoprotein (oxLDL) and is important in vessel remodeling. S-1-P will act...

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Detalhes bibliográficos
Main Authors: Duru, Enrico A., Fu, Yuyang, Davies, Mark G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392410/
https://ncbi.nlm.nih.gov/pubmed/22480845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2011.12.012
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