Androgen metabolism and JAK/STAT pathway genes and prostate cancer risk

BACKGROUND: Prostate cancer (PC) is the most frequently diagnosed solid tumor in U.S. men. Genome-wide association studies (GWAS) have identified over 40 risk-associated single nucleotide polymorphisms (SNPs), including variants in androgen pathway genes (e.g., KLK3 and AR). Androgens are important...

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Main Authors: Kwon, Erika M., Holt, Sarah K., Fu, Rong, Kolb, Suzanne, Williams, Gabrielle, Stanford, Janet L., Ostrander, Elaine A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392409/
https://ncbi.nlm.nih.gov/pubmed/22542949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canep.2012.04.002
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