Angiotensin II-Induced Mitochondrial Nox4 Is a Major Endogenous Source of Oxidative Stress in Kidney Tubular Cells

Angiotensin II (Ang II)-induced activation of nicotinamide adenine dinucleotide phosphate (NAD(P)H) oxidase leads to increased production of reactive oxygen species (ROS), an important intracellular second messenger in renal disease. Recent findings suggest that Ang II induces mitochondrial depolari...

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Main Authors: Kim, Su-Mi, Kim, Yang-Gyun, Jeong, Kyung-Hwan, Lee, Sang-Ho, Lee, Tae-Won, Ihm, Chun-Gyoo, Moon, Ju-Young
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392275/
https://ncbi.nlm.nih.gov/pubmed/22808054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039739
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