Angiotensin II-Induced Mitochondrial Nox4 Is a Major Endogenous Source of Oxidative Stress in Kidney Tubular Cells

Angiotensin II (Ang II)-induced activation of nicotinamide adenine dinucleotide phosphate (NAD(P)H) oxidase leads to increased production of reactive oxygen species (ROS), an important intracellular second messenger in renal disease. Recent findings suggest that Ang II induces mitochondrial depolari...

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Autores principales: Kim, Su-Mi, Kim, Yang-Gyun, Jeong, Kyung-Hwan, Lee, Sang-Ho, Lee, Tae-Won, Ihm, Chun-Gyoo, Moon, Ju-Young
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392275/
https://ncbi.nlm.nih.gov/pubmed/22808054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039739
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