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Angiotensin II-Induced Mitochondrial Nox4 Is a Major Endogenous Source of Oxidative Stress in Kidney Tubular Cells

Angiotensin II (Ang II)-induced activation of nicotinamide adenine dinucleotide phosphate (NAD(P)H) oxidase leads to increased production of reactive oxygen species (ROS), an important intracellular second messenger in renal disease. Recent findings suggest that Ang II induces mitochondrial depolari...

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Detalhes bibliográficos
Main Authors: Kim, Su-Mi, Kim, Yang-Gyun, Jeong, Kyung-Hwan, Lee, Sang-Ho, Lee, Tae-Won, Ihm, Chun-Gyoo, Moon, Ju-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392275/
https://ncbi.nlm.nih.gov/pubmed/22808054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039739
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